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Recessive dystrophic epidermolysis bullosa ( RDEB ) results from deficiency of type VII collagen ( C7 ), which results in lack of attachment between the epidermis and dermis, severe blistering, and a ...


The Committee for Medicinal Products for Human Use ( CHMP ) has recommended marketing authorisation for Maci ( matrix-induced autologous chondrocyte implantation ), an advanced-therapy medicinal produ ...


A study has identified a previously unrecognized mutation that causes an inherited form of amyotrophic lateral sclerosis ( ALS ). The research, published in the journal Neuron, implicates defects in ...


Genetic variations in the Sonic Hedgehog pathway increase the likelihood of recurrence, reduce survival time and limit response to therapy for people with non-muscle invasive bladder cancer.These vari ...


The first operation for transplantation of a tissue-engineered airway has been successful, and has massively improved the quality of life of the 30-year-old Colombian female recipient, a mother of two ...


The FDA ( Food and Drug Administration ) has approved a drug to help ease the suffering faced by those with certain chronic inflammatory diseases. Arcalyst ( Rilonacept, an Interleukin-1 blocker ) is ...


A gene therapy treatment that restores a missing liver enzyme in test animals could provide a cure for a rare metabolic disorder in humans. People born with the disorder, called glycogen storage ...


Immune cells that would normally die in healthy people accumulate in bodies of patients who have lupus and contribute to the disease, according to new research published in the Immunity. The findin ...


A rare disorder caused by an excess of two types of immune cells, the mast cell found in various tissues and its blood-based twin, the basophil, has successfully been treated with a cancer drug, repor ...


The endocannabinoid system was discovered through research into delta 9-tetrahydrocannabinol ( 9-THC ), the active ingredient in cannabis. The endocannabinoid system consists of cannabinoid recepto ...


A Glucosamine-like dietary supplement has been found to suppress the damaging autoimmune response seen in multiple sclerosis and type-1 diabetes mellitus, according to University of California, Irvin ...


Researchers at the Kimmel Cancer Center at Jefferson in Philadelphia have discovered new molecular evidence of the role of the hormone prolactin in breast cancer. They have found that prolactin, a pi ...


Not all patients with sepsis mount the same immune response, even when they look the same clinically, according to findings from the first large-scale natural history study of sepsis. The results, pub ...


Researchers at the Massachusetts General Hospital ( MGH ) Cancer Center have discovered a novel gene mutation associated with Wilms tumor, the most common pediatric kidney cancer. The newly identifi ...


A large-scale genomic study has uncovered new genetic variations associated with multiple sclerosis, findings that suggest a possible link between multiple sclerosis and other autoimmune diseases. T ...